Type 1 Diabetes TrialNet

TrialNet is screening relatives of people with Type 1 Diabetes to find out if these family members are at risk for developing diabetes.

Screening

-Screening involves a simple blood test for the presence of diabetes-related autoantibodies that may appear years before Type 1 diabetes develops.

-You may be screened to determine your risk of diabetes if

#1 You are between 1 and 45 years of age and are a first-degree blood relative (sibling, child or parents) of a person with type 1 diabetes

OR

#2 If you are between 1 and 20 years of age and have a second degree blood relative (cousin, uncle, aunt, niece, nephew, grandparent or half-sibling) with Type 1 diabetes.

-Relatives of people with Type 1 diabetes have about a 3-4 percent chance of testing positive for autoantibodies associated with diabetes.

-There is no cost for the test.

How will you benefit from screening and further risk assessment?

-If you learn you are at risk for developing Type 1 diabetes, additional tests will be offered to estimate your chances of developing type 1 diabetes.

-If you qualify, you may have an opportunity to be enrolled in either a Natural History or Prevention Study.

-All research volunteers will be closely monitored for early detection for Type 1 diabetes.

-Early detection of Type 1 diabetes may improve your blood sugar control and reduce your chances of developing complications.

-You will be part of a research program that may help other people at risk for Type 1 diabetes.

Natural History Studies

-Natural history studies are being done to learn more about what causes Type 1 diabetes and to better define predictors of the disease process.

-These studies provide close monitoring to individuals at risk for developing Type 1 diabetes.

-Individuals who qualify may be offered an opportunity to participate in a prevention study.

Diabetes Prevention Studies

-Diabetes prevention studies are being planned to determine whether new therapies can delay, or prevent, the onset of Type 1 diabetes in “at-risk” individuals.

-If you are enrolled in a prevention trial, your development of diabetes may be delayed or prevented, if the therapy being tested is successful

If you have anymore questions or want more information, please contact Martha Halsey-Lyda toll free at 877-880-4007 or mhlyda@childrensmemorial.com

The Type 1 Diabetes Genetic Consortium

What is the Type 1 diabetes consortium?

The consortium is a group of diabetes researchers from around the world who have come together to collect samples and information from families with Type 1 diabetes.

What is the consortium trying to do?

We are trying to discover how differences in the genes that we inherit from our parents contribute to the risk of development of Type 1 diabetes. Genes are the “blue prints” in our bodies that we get from our parents at birth. Genes decide our characteristics like the color of our hair, our eyes and the shape of our bodies. Some genes are also involved in whether you have diabetes or not. If we find out more about these genes, we may be able to prevent diabetes in the future.

Who can participate?

We are looking for Mexican-American or African-American families in which there is ONE child with diabetes. In these families, we would like the participation of the child with diabetes and both parents.

What you will need to do:

If you want to help us, we will take some blood and ask you some questions about your diabetes and your health.

What is being done with my blood?

The blood will go to laboratories where scientists will study the genes in the cells of the blood. The blood will be prepared in such a way that you do not need to come back in the future.

What do I do next?

If you have any/more questions or want more information, please contact Martha Halsey-Lyda toll free at 877-880-4007 or mhlyda@childrensmemorial.com