Special Infectious Diseases - HIV /AIDS

• Research Opportunities
  Children's HIV/AIDS Program is the leader in Chicago to provide patients with the opportunity to enroll in pediatric or adolescent HIV/AIDS clinical research studies sponsored by the National Institutes of Health. Children's HIV/AIDS Program offers patients access to the latest medication and treatment available. This research will continue to:
         * Advance the standards of HIV care significantly 
              * Improve the quality of life for HIV infected patients 
                     * Reduce new infection rates
  Children's HIV/AIDS Program is one of the top rated pediatric HIV research sites in the country with more than 185 patients enrolled in government sponsored clinical trials.
  
  In addition, Children’s HIV/AIDS Program participates in numerous pharmaceutical company’s clinical research studies that strive to improve medication alternatives for HIV patients. These studies afford our patients access to cutting-edge research and medications that are designed to improve their quality of life until effective vaccines and a cure are found.
  
• Advanced Laboratories
  Children's HIV/AIDS Program has an on-site laboratory certified in various HIV tests from which we can obtain tests faster than any other institution in the Chicago area. Our lab has become one of the top rated pediatric HIV/AIDS labs in the country. In fact, the advanced on-site lab at Children's Memorial provides pediatric HIV testing for Cook County Hospital, the University of Chicago, Loyola University Medical Center, Lutheran General Hospital, Mt. Sinai Hospital, and other institutions. 
  
  

   

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Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected Children 
Interventions: Drug: Atazanavir; Darunavir; Efavirenz; Nevirapine; Ritonavir; Tenofovir disoproxil fumarate;
Procedure: Pharmacokinetic Study
Principal Investigator: Ram Yogev, MD and Ellen Chadwick, MD 
Contact: Eric Cagwin
Phone: 773-880-3669
Email: ecagwin@childrensmemorial.org  
IRB Number: 2008-13365 (ClinicalTrials.gov identifier: NCT00260078)

Safety and Effectiveness of Raltegravir (MK-0518) in Treatment-Experienced, HIV-Infected Children and Adolescents 
Interventions: Drug: Raltegravir (MK-0518)
Principal Investigator: Ellen Chadwick, MD and Ram Yogev, MD
Contact: Eric Cagwin
Phone: 773-880-3669
Email: ecagwin@childrensmemorial.org  
IRB Number: 2007-13231 (ClinicalTrials.gov identifier: NCT00485264)

Early Initiation of HAART 
Condition: HIV Infections
Interventions: Procedure: Early Initiation of Highly Active Anti-Retroviral Therapy; Standard Care
Principal Investigator: Robert Garofalo, MD, MPH and Ram Yogev, MD 
Contact: Eric Cagwin, BSN
Phone: 773-880-3669
Email: ecagwin@childrensmemorial.org  
IRB Number 2007-13264( ATN 061; ClinicalTrials.gov identifier: NCT00491556)

Vitamin D Reabsorption in Adolescents and Young Adults with HIV Infection 
Condition: HIV Infections
Interventions: Dietary Supplement: Vitamin D supplement; Other: Placebo
Principal Investigator: Robert Garofalo, MD, MPH and Ram Yogev, MD 
Contact: Eric Cagwin, BSN
Phone: 773-880-3669
Email: ecagwin@childrensmemorial.org  
IRB Number 2008-13311 (ATN 063; ClinicalTrials.gov identifier: NCT00490412)

Neurocognitive Assessment and HAART 
Condition: HIV Infections
Interventions: Drug: Early Treatment with HAART; Other: No treatment; Drug: HAART Treatment - standard care
Principal Investigator: Robert Garofalo, MD, MPH and Ram Yogev, MD 
Contact: Eric Cagwin, BSN
Phone: 773-880-3669
Email: ecagwin@childrensmemorial.org  
IRB Number 2008-13412 (ATN 071; ClinicalTrials.gov identifier: NCT00683579)

Psychosocial Needs of YMSM 
Condition: HIV+ YMSM
Principal Investigators: Robert Garofalo, MD and Ram Yogev, MD 
Phone: 773-388-8661
Email: ecagwin@childrensmemorial.org  
IRB Number 2008-13494 (ATN 070; ClinicalTrials.gov identifier: NCT00710671) 

Prenatal and Postnatal Studies of Interventions for Prevention of Mother-To-Child Transmission
Principal Investigator: Debbie Fonken-Cloutier, RN, BS
Phone:  773-880-3669 
Email:  dcloutie@childrensmemorial.org 
Clinical Trials.gov NCT00028145