Profile

  

Hans-Georg Simon, Ph.D.
Bernard L. Mirkin Research Scholar

Associate Professor
Department of Pediatrics
Northwestern University Feinberg School of Medicine
Developmental Biology Program

Director of Predoctoral and Postdoctoral Research Training Program
Children's Memorial Research Center

hgsimon@northwestern.edu   

2300 Children's Plaza
Box 204 Room 421C
Chicago, IL 60614-4314
Phone: (773) 755-6391
Fax: (773) 755-6385 
 

 

Education 
 

Year  Degree  Institution 
1988-92 Postdoctral Fellow Harvard Medical School, Boston, USA 
1988 Ph.D.  University of Freiburg, Germany   
1983 Diploma University of Heidelberg, Germany 

 

Lab Affiliations
Simon Lab



Recent Publications  

 

Camarata, T., Snyder, D., Schwend, T., Klosowiak, J., Holtrup, B., Simon H.G. Pdlim7 is required for maintenance of the mesenchymal/epidermal Fgf signaling feedback loop during zebrafish pectoral fin development. BMC Dev. Biol. 10:104 (2010).  

Calve, S., Odelberg, S.J., Simon, H.G. A transitional extracellular matrix instructs cell behavior during muscle regeneration. Dev. Biol. 344(1) 259-71 (2010)   

Krcmery, J., Camarata, T., Kulisz, A., Simon, H.G. Nucelocytoplasmic functions of the PDZ-LIM protein family: new insights into organ development. Bioessays 32(2), 100-8 (2010)  

Camarata, T., Krcmery, J., Snyder, D., Park, S., Topczewski, J., Simon, H.G. Pdlim7 (LMP4) regulation of TBx5 specifies zebrafish heart atrio-ventricular boundary and valve formation.  Dev. Biol. 337(2) 233-45 (2010).    

Kulisz, A., Simon, H-G. An evolutionary conserved nuclear export signal facilitates cytoplasmic localization of the Tbx5 transcription factor. Mol. Cell. Biol. 28, 1553-1564 (2008)

Bimber, B., Dettman, R., Simon, H.G. Differential regulation of Tbx5 protein expression and sub-cellular localization during heart development. Dev. Biol. 302, 230-242 (2007).

Camarata, T., Bimber, B., Kulisz, A., Yeung, J., Chew, T.L., and Simon, H. G. LMP4 regulates Tbx5 protein sub-cellular localization and activity. J. Cell. Biol. 174, 339-348 (2006).

Isphording, D., Leylek, A.L., Yeung, J., Mischel, A., and Simon, H.-G. T-box genes and congenital heart/limb malformations. Clin. Genet. 66, 253-264 (2004).  

Krause, A., Zacharias, W., Linkhart, B., Camarata, T., Law, E., Lischke, A., Miljan, E., Simon, H.-G. Tbx5 and Tbx4 Transcription factors interact with a new chicken PDZ-LIM protein in limb and heart development. Dev. Biol. 273, 106-120 (2004).