Stem Cell Transplantation

For information on the following Clinical Trials, please contact the
Hematology, Oncology and Stem Cell Transplantation Department
at 773-880-4562 during 8:30 AM to 5:00 PM Central Standard Time.

 

  General Transplant Protocols:   Investigator 
SCT 0193 General Bone Marrow/SCT Research Morris Kletzel, MD
SCT 0511 A Multicenter Study of Hematopoietic Stem Cell Donor Safety and Quality of Life William Tse, MD
SCT 0810     A Prospective Natural History Study of Diagnosis, Treatment and Outcomes of Children with SCID Disorders Morris Kletzel, MD
     
  Allo Transplant Protocols:   Investigator 
SCT 0208 Allogeneic Transplanation for Pediatric Leukemias with Unrelated Donors Using Fludarabine, Busulfan, 400 cGy Total Body Irradiation, and Thymogobulin Sonali Chaudhury, MD
SCT 0300-0406 Reduced Intensity Immunoablative Protocol for Allogeneic Related and Unrelated Hemotopoietic Peripheral Blood Stem Morris Kletzel, MD
SCT 0307 Full Intensity Myeloid & Lymphoid Myeloablative Hematopoietic Progenitor Cell Transplantation (HPCT) for Pediatric Malignancies Morris Kletzel, MD
SCT 0310

 

 		 A Study of Hematopoietic Stem Cell Transplantation (HSCT) in Non-malignant Diseases Using a Reduced-intensity Preparatory Regime with Campath-1H, Fludarabine and Melphalan  Sonali Chaudhury, MD
SCT 0411 The Role of Minimal Residual Disease Testing Before and After Hematopoietic Cell Transplantation for Pediatric Acute Myeloid Leukemia: A Comparison of Flow Cytometry and WT1 PCR Testing Morris Kletzel, MD
SCT 0508 A Multi-Center, Mutli-National, Historical Cohort Controlled Study to Evaluate Efficacy and Safety of Transplantation of StemEx®, Umbilical Cord Blood Stem and Progenitor Cells Expanded Ex Vivo, in Subjects with Hematologic Malignancies following Myeloablative Therapy Sonali Chaudhury, MD
SCT 0608 BMT CTN 0601: Unrelated Donor Hematopoietic Cell Transplantation for Children with Severe Sickle Cell Disease using a Reduced Intensity Conditioning Regimen Reggie Duerst, MD
SCT 0707 Early Diagnosis and Stem Cell Transplantation for Severe Immunodeficiency Diseases (SCIDS) William Tse, MD
SCT 0709 A Pilot Trial of Unrelated Donor Hematopoietic Cell Transplantation for Children with Severe Thalassemia Using a Reduced Intensity Conditioning Regimen (The URTH Trial) Sonali Chaudhury, MD
SCT 0711 Protocol 10-CBA: A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications Reggie Duerst, MD
SCT 1209b A Pilot Study of Sequential Myeloblative Stem Cell Transplantation and Reduced Intensity Allogeneic Stem Cell Transplantation Followed by Adoptive Cellular Immunotherapy (only in patients with matched family donors and unrelated adult donors) in Patients with Refractory or Recurrent Non-Hodgkin's Lymphoma and Hodgkin's Disease Sonali Chaudhury, MD
ASCT0431 A Randomized Trial of Sirolimus-Based Graft versus Host Disease Prophylaxis after Hematopoietic Stem Cell Transplantation in Relapsed ALL Reggie Duerst, MD
     
  Auto Transplant Protocols:  Investigator 
SCT 0308 High dose temozolomide, thiotepa and carboplatin with autologous stem cell rescue (ASCR) followed by continuation therapy with 13-cis-retinoic acid in patients with recurrent/refractory maligant brain tumors Reggie Duerst, MD
SCT 0499 Solid Tumor High Dose Chemotherapy with Tandem Peripheral Blood Stem Cell Rescue for the Treatment of High Risk Pediatric Solid Tumors Morris Kletzel, MD
     
  GVHD Protocols:  Investigator 
SCT 0108 Chronic GVHD Natural History Cohort Study David Jacobsohn, MD
SCT 0208b Development and Validation of a Symptoms Scale for Children with Chronic Graft Versus Host Disease David Jacobsohn, MD
SCT 0708 Expanded Access of ProchymalTM (Ex-vivo Cultured Adult Human Mesenchymal Stem Cells) Infusion for the Treatment of Pediatric Patients who have failed to respond to steriod treatment for acute GVHD Sonali Chaudhury, MD
SCT 1109 A Multi-Center, Randomized, Double Blind, Phase 3 Trial Evaluating Corticosteroids with Mycophenolate Mofetil versus Corticosteroids with Placebo as Initial Systemic Treatment of aGVHD David Jacobsohn, MD
     
  Supportive Care Protocols:  Investigator 
SCT 0408B     Defibrotide for Patients with hepatic Veno-Occlusive Disease (VOD): A Treatment IND Study Reggie Duerst, MD
SCT 1006 Defibrotide Defibrotide for the Treatment of severe Veno-Occlusive Disease (Amend 3.0) Reggie Duerst, MD
ASCT0521 Soluble Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for the Treatment of Acute, Non-infectious Pulmonary Dysfunction (Idiopathic Pneumonia Syndrome)
 		 David Jacobsohn, MD
SCT 1107 Polymorphism and Busulfan PK's Morris Kletzel, MD
     
  Other Stem Cell Protocols:  Investigator 
SCT 0599 Procurement of Umbilical Cord Hematopoietic Stem Cells (UCHSC) for Laboratory Research Purposes Morris Kletzel, MD
SCT 0610 Xenobase Project: Outcomes for SCT Patients in the PICU Sonali Chaudhury, MD
SCT 0611 Primary Immune Deficiency Treatment Consortium: Protocol #6902: A Retrospective and Cross-Sectional Analysis of Patients Treated for SCID Morris Kletzel, MD
SCT 1099 Longitudinal Study of Immune Mediated Disorders after Allogeneic HCT David Jacobson, MD
SCT 1109b Population pharmacokinetic-pharmacodynamic analysis of the efficacy-safety of busulfan Morris Kletzel, MD
SCT 1207D NMDP & CIBMTR Research Protocol for a Research Database for Hematopoietic Stem Cell Transplantation and Marrow Toxic Injuries Reggie Duerst, MD
SCT 1207R NMDP Protocol for a Research Sample Repository for Allogeneneic Hematopoietic Stem Cell Transplantation Reggie Duerst, MD