Job Opportunities
Human Molecular Genetics Program - Current Job Openings
1) Post-doctoral Fellowship
Applications are invited for a post-doctoral position to investigate the transcriptome of airway epithelial cells, aiming to identify molecular markers that are key to diseases of the airway. Successful applicants for this NHLBI-funded program will be highly motivated, possess excellent graduate training, and have a good publication record.
The project will use genome-wide approaches to investigate signatures of differentiation of the airway epithelium, including expression analysis by microarray and identification of regulatory elements by whole genome sequencing. Experiments will involve cell biology, biochemistry, and molecular biology to study primary airway epithelial cells. Expertise in any of the above methods and/or in bioinformatics is required. We are part of a vibrant and interactive academic community and occupy excellent, well-equipped new laboratory space.
Please send a letter of application, quoting the reference CMRC/AH/0911ii, curriculum vitae, and contact information of three referees to c-pomeroy@northwestern.edu. E-mail is preferred, but if you must send a hard copy, please send it to:
Chris Pomeroy
Program Assistant
Human Molecular Genetics Program
Children's Memorial Research Center
2300 Children's Plaza (Box 211)
Chicago, IL 60614
Hiring is contingent upon eligibility to work in the United States. Women and minority candidates are strongly encouraged to apply.
Updated November 2009
2) Post-doctoral Fellowship
Applications are invited for a post-doctoral position to investigate the chromatin structure and tissue-specific regulation of expression of the CFTR gene, which when mutated causes Cystic Fibrosis. This NHLBI-funded project will build on our recent work on the CFTR active chromain hub (Blackledge et al. 2009 Nucleic Acids Research 37(4): 1086-94); (OTT et al. 2009. J. Cell. Mol. Med. 13(4): 680-92; Ott et al. PNAS, In Press). Successful applicants will be highly motivated, possess excellent graduate training, and have a good publication record.
The project will involve elucidating the function of elements that we have identified, which regulate expression of the CFTR gene in human epithelial cells. These include enhancer blocking insulators, tissue specific enhancers and other genetic elements. In addition, we are using genome-wide approaches to investigate signatures of tissue specific regulation of other markers of differentiation of the airway epithelium. Experiments will involve in vitro and in vivo analysis of regulatory sequences (by chromatin immunoprecipitation, transcription factor modulation, chromosome conformation capture, DNA pull down and bioinformatics).
Expertise in methods to study chromatin structure and modificaiton, and/or transcription factors, through the analysis of DNA:protein interactions is necessary. Familiarity with bioinformatic tools is an advantage. We are part of a vibrant and interactive academic community and occupy excellent, well-equipped new laboratory space.
Please send a letter of application (quoting the reference CMRC/AH/9011), curriculum vitae, and contact information of three referees to c-pomeroy@northwestern.edu. E-mail is preferred, but if you must send a hard copy, please send it to:
Chris Pomeroy
Program Assistant
Human Molecular Genetics Program
Children's Memorial Research Center
2300 Children's Plaza (Box 211)
Chicago, IL 60614
Hiring is contingent upon eligibility to work in the United States. Women and minority candidates are strongly encouraged to apply.
Updated November 2009