Jared Bischof

Jared Bischof
	Senior Software Engineer

Education
	Year	Degree	Institution
	2010	M.S. - Computational Biology and Bioinformatics	Northwestern University
	2005	M.S. - Electrical and Computer Engineering	University of Iowa
	2003	B.S. - Electrical and Computer Engineering	University of Iowa

Work Experience
	Period	Description	Organization
	August 2008 - present	Senior Software Engineer	Children's Memorial Research Center, Cancer Biology and Epigenomics
	May 2005 - August 2008	Application Specialist	Children's Memorial Research Center, Cancer Biology and Epigenomics
	January 2005 - May 2005	Teaching Assistant	University of Iowa
	May 2001 - May 2005	Research Assistant	Coordinated Laboratory for Computational Genomics at the University of Iowa

Publications
	Sredni ST, Bonaldo Mde F, Costa FF, Huang CC, Hamm CA, Rajaram V, Tomita T, Goldman S, Bischof JM, Soares MB. 2010. Upregulation of mir-221 and mir-222 in atypical teratoid/rhabdoid tumors: potential therapeutic targets. Childs Nerv Syst 26(3):279-283.
	Hamm CA, Xie H, Costa FF, Vanin EF, Seftor EA, Sredni ST, Bischof J, Wang D, Bonaldo MF, Hendrix MJ and others. 2009. Global demethylation of rat chondrosarcoma cells after treatment with 5-aza-2'-deoxycytidine results in increased tumorigenicity. PLoS One 4(12):e8340.
	Costa FF, Seftor EA, Bischof JM, Kirschmann DA, Strizzi L, Arndt K, Bonaldo Mde F, Soares MB, Hendrix MJ. 2009. Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment. Epigenomics 1(2):387-398.
	Lewandowska MA, Costa FF, Bischof JM, Williams SH, Soares MB, Harris A. 2009. Multiple Mechanisms Influence Regulation of the CFTR Gene Promoter. Am J Respir Cell Mol Biol.
	Xie H, Wang M, Bischof J, Bonaldo Mde F, Soares MB. 2009. SNP-based prediction of the human germ cell methylation landscape. Genomics 93(5):434-440.
	Postovit LM, Costa FF, Bischof JM, Seftor EA, Wen B, Seftor RE, Feinberg AP, Soares MB, Hendrix MJ. 2007. The commonality of plasticity underlying multipotent tumor cells and embryonic stem cells. J Cell Biochem 101(4):908-917.
	Bischof JM, Chiang AP, Scheetz TE, Stone EM, Casavant TL, Sheffield VC, Braun TA (June, 2006). Genome-wide identification of pseudogenes capable of disease-causing gene conversion. Human Mutation: 545-552.
	Scheetz TE, Berger B, Bischof JM, Bonaldo MF, Casavant TL, Sheffield VC, Soares MB and others (April, 2004). High-throughput gene discovery in the rat. Genome Research: 733-741.
	Trivedi N, Bischof JM, Davis S, Pedretti K, Scheetz TE, Braun TA, Roberts CA, Robinson NL, Sheffield VC, Soares MB and Casavant TL (May, 2002). Parallel creation of non-redundant gene indices from partial mRNA transcripts. Future Generation Computer Systems: 863-870.

Websites
	Bioinformatics Portal (internal use only) UI Pseudogenes

Biography

Jared attended the University of Iowa and completed his B.S. and M.S. there in Electrical and Comptuer Engineering. During that time, he spent five years working for the Coordinated Laboratory for Computational Genomics (CLCG) where he began to delve into the fields of bioinformatics and computational biology. While a member of the CLCG, Jared collaborated with various labs and participated in numerous projects including among others: EST processing and clustering of ESTs, development of an application to view intervals on a chromosomal level, microRNA binding site prediction, pseudogene identification and ranking of pseudogenes as candidates for gene conversion.

Jared was hired as an Application Specialist in Dr. Soares' lab in 2005 and promoted to Senior Software Engineer in 2008. He is again involved in a number of research projects. Some of these include studying the functional significance of genomic alterations in pediatric ependymomas, investigating the role of Alu recombination-mediated rearrangements in cancer, and looking at correlates between genomic methylation and recombination effects. He also completed his second master's degree in 2010 at Northwestern University in the Computational Biology and Bioinformatics program.