CMRC Children's Memorial Research Center
Topczewski Laboratory

Hot News:

Dr. Barbara Sisson was awarded Ruth L. Kirschstein National Research Service Scholarship from the NIH/National Institute Dental and Craniofacial Research.  Congratulations!




The Topczewski laboratory investigates the mechanisms that control the morphogenetic processes of vertebrate embryos, by using zebrafish as a model.  Similarities in developmental programs among all vertebrates make zebrafish an excellent model for studying human diseases and development.  In our work we utilize a combination of genetic analysis with embryological and molecular methods uniquely available in zebrafish. Our long-term goal is the identification of signaling pathways that will suggest novel candidate genes involved in human congenital abnormalities and diseases.