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Why use zebrafish as a model?
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Small, cheaply maintained
Lay hundreds of eggs at weekly intervals
Short generation time 2-3 months
Easy to perform large scale forward-genetic analysis
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Externally fertilized
Accessible to observation and manipulation from the moment of fertilization
Manipulation of gene activity by oligonucledide, RNA and DNA injection
Generation of transgenic animals
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Fate mapping
Fluorescent tracer time-lapse lineage analysis
Single cell transplantation
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To learn more about research using zebrafish go to:
The Zebrafish Information Network web site.
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